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SMART IONIC SHIELD  

A next-gen antimicrobial polymer
that protects skin fast - and gently.

Destroys harmful microbes within seconds while remaining skin-friendly for daily use.

Exclusively licensed from A*STAR Singapore, Smart Ionic Shield Technology is a next-generation antimicrobial breakthrough. It's macromolecular structure forms a long-lasting protective barrier on the skin, defending against a broad spectrum of harmful microbes while keeping the skin nourished, hydrated and healthy. 

Addressing the Antimicrobial Resistance Crisis

Antimicrobial resistance (AMR) occurs when microbes no longer respond to treatment, making infections harder to cure and increasing illness and death risks (World health Organization).

Trisafe’s polyionene technology offers a novel way to combat AMR. Unlike antibiotics or small-molecule antiseptics that drive resistance through overuse, polyionenes disrupt microbial membranes—minimizing the chance of resistance.

As macromolecules, they don’t penetrate the skin, ensuring safety with low irritation risk. Combined with their fast, broad-spectrum action, polyionenes are perfect for both clinical and consumer healthcare use.

How it works? 

Physical action, fast results.

Unique properties 

Broad spectrum

effective against bacteria, fungi and virus. 

Fast acting

Eliminate microbes within 30 secs. 

Mitigate drug resistance

Unique membrane-lytic mechanism to prevent development of resistance. 

Long lasting

Offer continuous protection for up to 48 hours after application. 

Safety

Safe on mammalian cells 

Multivalent positive charge that makes it highly selective towards microbes over human cells. 

Safe on skin and body

Macromolecular structure which does not penetrate skin to cause systemic side effects and irritation. 

Safe on environment

Amide-bonded that is stable under storage condition yet biodegradable by environmental enzymes. 

Evidence & numbers. 

Validated by independent labs and safety standards.

Lab Validated Skin Compatibility Test

Polyionene formula preserves skin's overall structure and cellular integrity. 

Validated Safety Tests

●Acute Skin Irritation (OECD 404)

No obvious irritation or adverse effects on skin

 

●Acute Eye Irritation (OECD 405)

No obvious irritation or adverse effects on the eyes

 

●Acute Skin Toxicity (OECD 402)

Passed

 

●Acute Oral Toxicity (OECD 425)

Passed

●Acute Inhalation Toxicity (OECD 436)

Not classified as hazardous

●Acute Systemic Toxicity

(ISO10993-11)

No adverse biological reactions​​

●Mutagenicity studies  (OECD 471)

No mutagenic potential

 

●Human Repeat Patch Test (HRIPT)

No irritation or allergy on human skin                             

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